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Gel Permeation Chromatography (GPC)

GPC is used for sample clean-ups to remove large bio-molecules such as fats from smaller, analyte molecules. The GPC column contains molecular sized pores which retain small molecules but lets larger molecules pass through without being retained. This technique can be used in pharmaceutical and environmental analyses to help remove interferences or improve the longevity of GC or LC columns used in subsequent sample analysis.

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